Sunday, May 23, 2010

Heart Failure?

How could you categorise the effects of heart failure on skeletal muscle dysfunction, i.e structural changes, metabolic pathways.
What headings could all the changes be placed under. Im writing a project and need to place each individual change into its own grouping.
Answers:
I found this..but don't know when it was updated last..
http://cpmcnet.columbia.edu/news/in-vivo.this is done on rates.I don't know .I hope it would be helpfull
http://www.medscape.com/medline/abstract.this is the most recent I found.."Vascular rarefaction in peripheral skeletal muscle after experimental heart failure "
http://ajpheart.physiology.org/cgi/conte.good luck
i dont think there r any structural changes in skeletal muscle
but since O2 delivery is hampered there is more of anaerobic cellular respiration leading to mild lactic acidosis causing fatigue %26 weakness

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